ea0094p378 | Reproductive Endocrinology | SFEBES2023
Fenn Jonathan
, Gill Henry
, Starbrook Lauren
, Sharrod-Cole Hayley
, Kalaria Tejas
, Ford Clare
, Gama Rousseau
Background: The diagnosis of male hypogonadism can be difficult. Free testosterone is calculated if total testosterone is close to the lower limit of normal, however, this is inaccurate in conditions that alter sex-hormone-binding globulin. Alternatively, salivary testosterone is thought to reflect free testosterone, but is present at low concentrations, thus requiring sensitive mass spectrometry instrumentation, and there is limited data on the pre-analytical...